Who wins Yasuo vs Zed Mid Lane in Patch 16.5?

In Patch 16.5 Emerald+ ranked games, Yasuo has a 48.7% win rate and Zed has a 51.5% win rate in Mid Lane. Zed has the statistical edge with a 2.8% win rate advantage.

How do I play the Yasuo vs Zed matchup?

Use Meridian Zero's matchup analysis tool for detailed trading patterns, power spike windows, and win conditions for Yasuo vs Zed in Mid Lane. Both champions' optimal builds, runes, and skill orders are shown on this page.

Yasuo vs Zed Mid Lane

Q: What is the best build for Yasuo against Zed?

The optimal Yasuo build starts with Doran's Blade and Health Potion. Core items are Blade of the Ruined King, Infinity Edge, Mortal Reminder with Berserker's Greaves. Run Lethal Tempo from Precision with Resolve secondary.

Q: What is the best build for Zed against Yasuo?

The optimal Zed build starts with Long Sword and Refillable Potion. Core items are Youmuu's Ghostblade, Opportunity, Serylda's Grudge with Boots of Lucidity. Run Electrocute from Domination with Precision secondary.

Patch 16.5 · Emerald+ Ranked · Meridian Zero Data

In the Yasuo vs Zed Mid Lane matchup on Patch 16.5, Yasuo has a 48.7% win rate (A tier) while Zed has a 51.5% win rate (S+ tier) in Emerald+ ranked games. Zed has the statistical edge with a 2.8% win rate advantage. Below are the optimal builds, runes, and skill orders for both champions in this matchup, sourced from OP.GG Emerald+ data.

Source: OP.GG Emerald+ ranked data, Patch 16.5 · Last updated: March 2026 · Meridian Zero Analytics

Yasuo

A Tier 48.7% WR

StartDoran's BladeHealth Potion

CoreBlade of the Ruined KingInfinity EdgeMortal Reminder

BootsBerserker's Greaves

SpellsFlashIgnite

SkillsQ > E > W

KeystoneLethal Tempo

PrimaryPrecision

SecondaryResolve

Zed

S+ Tier 51.5% WR

StartLong SwordRefillable Potion

CoreYoumuu's GhostbladeOpportunitySerylda's Grudge

BootsBoots of Lucidity

SpellsFlashIgnite

SkillsQ > E > W

KeystoneElectrocute

PrimaryDomination

SecondaryPrecision

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Yasuo vs Zed Mid Lane

Yasuo

Zed

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