Nilah vs Kai'Sa Bot Lane

Patch 16.5 · Emerald+ Ranked · Meridian Zero Data

In the Nilah vs Kai'Sa Bot Lane matchup on Patch 16.5, Nilah has a 54.9% win rate (S+ tier) while Kai'Sa has a 49.1% win rate (S tier) in Emerald+ ranked games. Nilah has the statistical edge with a 5.8% win rate advantage. Below are the optimal builds, runes, and skill orders for both champions in this matchup, sourced from OP.GG Emerald+ data.

Source: OP.GG Emerald+ ranked data, Patch 16.5 · Last updated: March 2026 · Meridian Zero Analytics

Nilah

Nilah

S+ Tier 54.9% WR
StartDoran's BladeHealth Potion
CoreTrinity ForceSterak's GageDeath's Dance
BootsPlated Steelcaps
SpellsFlashHeal
SkillsQ > E > W
KeystonePress the Attack
PrimaryPrecision
SecondaryDomination
Kai'Sa

Kai'Sa

S Tier 49.1% WR
StartDoran's BladeHealth Potion
CoreInfinity EdgePhantom DancerBloodthirster
BootsBerserker's Greaves
SpellsFlashHeal
SkillsQ > W > E
KeystoneLethal Tempo
PrimaryPrecision
SecondaryDomination

Get Full Matchup Intelligence

Detailed trading patterns, power spikes, gold differentials, and AI-powered win conditions for Nilah vs Kai'Sa.

Analyze This Matchup Free View Pro Plans