Who wins Nautilus vs Zilean Support in Patch 16.5?

In Patch 16.5 Emerald+ ranked games, Nautilus has a 48.8% win rate and Zilean has a 50.5% win rate in Support. Zilean has the statistical edge with a 1.7% win rate advantage.

How do I play the Nautilus vs Zilean matchup?

Use Meridian Zero's matchup analysis tool for detailed trading patterns, power spike windows, and win conditions for Nautilus vs Zilean in Support. Both champions' optimal builds, runes, and skill orders are shown on this page.

Nautilus vs Zilean Support

Q: What is the best build for Nautilus against Zilean?

The optimal Nautilus build starts with Relic Shield and Health Potion. Core items are Locket of the Iron Solari, Knight's Vow, Zeke's Convergence with Plated Steelcaps. Run Guardian from Resolve with Inspiration secondary.

Q: What is the best build for Zilean against Nautilus?

The optimal Zilean build starts with Spellthief's Edge and Health Potion. Core items are Blackfire Torch, Rylai's Crystal Scepter, Morellonomicon with Sorcerer's Shoes. Run Summon Aery from Sorcery with Resolve secondary.

Patch 16.5 · Emerald+ Ranked · Meridian Zero Data

In the Nautilus vs Zilean Support matchup on Patch 16.5, Nautilus has a 48.8% win rate (S tier) while Zilean has a 50.5% win rate (A tier) in Emerald+ ranked games. Zilean has the statistical edge with a 1.7% win rate advantage. Below are the optimal builds, runes, and skill orders for both champions in this matchup, sourced from OP.GG Emerald+ data.

Source: OP.GG Emerald+ ranked data, Patch 16.5 · Last updated: March 2026 · Meridian Zero Analytics

Nautilus

S Tier 48.8% WR

StartRelic ShieldHealth Potion

CoreLocket of the Iron SolariKnight's VowZeke's Convergence

BootsPlated Steelcaps

SpellsFlashIgnite

SkillsQ > W > E

KeystoneGuardian

PrimaryResolve

SecondaryInspiration

Zilean

A Tier 50.5% WR

StartSpellthief's EdgeHealth Potion

CoreBlackfire TorchRylai's Crystal ScepterMorellonomicon

BootsSorcerer's Shoes

SpellsFlashIgnite

SkillsQ > W > E

KeystoneSummon Aery

PrimarySorcery

SecondaryResolve

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Nautilus vs Zilean Support

Nautilus

Zilean

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