Who wins Kai'Sa vs Yasuo Bot Lane in Patch 16.5?

In Patch 16.5 Emerald+ ranked games, Kai'Sa has a 49.1% win rate and Yasuo has a 51.6% win rate in Bot Lane. Yasuo has the statistical edge with a 2.5% win rate advantage.

What is the best build for Kai'Sa against Yasuo?

The optimal Kai'Sa build starts with Doran's Blade and Health Potion. Core items are Infinity Edge, Phantom Dancer, Bloodthirster with Berserker's Greaves. Run Lethal Tempo from Precision with Domination secondary.

How do I play the Kai'Sa vs Yasuo matchup?

Use Meridian Zero's matchup analysis tool for detailed trading patterns, power spike windows, and win conditions for Kai'Sa vs Yasuo in Bot Lane. Both champions' optimal builds, runes, and skill orders are shown on this page.

Kai'Sa vs Yasuo Bot Lane

Q: What is the best build for Yasuo against Kai'Sa?

The optimal Yasuo build starts with Doran's Blade and Health Potion. Core items are Blade of the Ruined King, Infinity Edge, Mortal Reminder with Berserker's Greaves. Run Lethal Tempo from Precision with Domination secondary.

Patch 16.5 · Emerald+ Ranked · Meridian Zero Data

In the Kai'Sa vs Yasuo Bot Lane matchup on Patch 16.5, Kai'Sa has a 49.1% win rate (S tier) while Yasuo has a 51.6% win rate (B tier) in Emerald+ ranked games. Yasuo has the statistical edge with a 2.5% win rate advantage. Below are the optimal builds, runes, and skill orders for both champions in this matchup, sourced from OP.GG Emerald+ data.

Source: OP.GG Emerald+ ranked data, Patch 16.5 · Last updated: March 2026 · Meridian Zero Analytics

Kai'Sa

S Tier 49.1% WR

StartDoran's BladeHealth Potion

CoreInfinity EdgePhantom DancerBloodthirster

BootsBerserker's Greaves

SpellsFlashHeal

SkillsQ > W > E

KeystoneLethal Tempo

PrimaryPrecision

SecondaryDomination

Yasuo

B Tier 51.6% WR

StartDoran's BladeHealth Potion

CoreBlade of the Ruined KingInfinity EdgeMortal Reminder

BootsBerserker's Greaves

SpellsFlashExhaust

SkillsQ > E > W

KeystoneLethal Tempo

PrimaryPrecision

SecondaryDomination

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Kai'Sa vs Yasuo Bot Lane

Kai'Sa

Yasuo

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