Who wins Caitlyn vs Yasuo Bot Lane in Patch 16.5?

In Patch 16.5 Emerald+ ranked games, Caitlyn has a 49.5% win rate and Yasuo has a 51.6% win rate in Bot Lane. Yasuo has the statistical edge with a 2% win rate advantage.

What is the best build for Caitlyn against Yasuo?

The optimal Caitlyn build starts with Doran's Blade and Health Potion. Core items are Infinity Edge, Phantom Dancer, Bloodthirster with Berserker's Greaves. Run Lethal Tempo from Precision with Domination secondary.

How do I play the Caitlyn vs Yasuo matchup?

Use Meridian Zero's matchup analysis tool for detailed trading patterns, power spike windows, and win conditions for Caitlyn vs Yasuo in Bot Lane. Both champions' optimal builds, runes, and skill orders are shown on this page.

Caitlyn vs Yasuo Bot Lane

Q: What is the best build for Yasuo against Caitlyn?

The optimal Yasuo build starts with Doran's Blade and Health Potion. Core items are Blade of the Ruined King, Infinity Edge, Mortal Reminder with Berserker's Greaves. Run Lethal Tempo from Precision with Domination secondary.

Patch 16.5 · Emerald+ Ranked · Meridian Zero Data

In the Caitlyn vs Yasuo Bot Lane matchup on Patch 16.5, Caitlyn has a 49.5% win rate (S tier) while Yasuo has a 51.6% win rate (B tier) in Emerald+ ranked games. Yasuo has the statistical edge with a 2% win rate advantage. Below are the optimal builds, runes, and skill orders for both champions in this matchup, sourced from OP.GG Emerald+ data.

Source: OP.GG Emerald+ ranked data, Patch 16.5 · Last updated: March 2026 · Meridian Zero Analytics

Caitlyn

S Tier 49.5% WR

StartDoran's BladeHealth Potion

CoreInfinity EdgePhantom DancerBloodthirster

BootsBerserker's Greaves

SpellsFlashHeal

SkillsQ > W > E

KeystoneLethal Tempo

PrimaryPrecision

SecondaryDomination

Yasuo

B Tier 51.6% WR

StartDoran's BladeHealth Potion

CoreBlade of the Ruined KingInfinity EdgeMortal Reminder

BootsBerserker's Greaves

SpellsFlashExhaust

SkillsQ > E > W

KeystoneLethal Tempo

PrimaryPrecision

SecondaryDomination

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Caitlyn vs Yasuo Bot Lane

Caitlyn

Yasuo

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