Who wins Brand vs Kai'Sa Bot Lane in Patch 16.5?

In Patch 16.5 Emerald+ ranked games, Brand has a 54.9% win rate and Kai'Sa has a 49.1% win rate in Bot Lane. Brand has the statistical edge with a 5.8% win rate advantage.

What is the best build for Kai'Sa against Brand?

The optimal Kai'Sa build starts with Doran's Blade and Health Potion. Core items are Infinity Edge, Phantom Dancer, Bloodthirster with Berserker's Greaves. Run Lethal Tempo from Precision with Domination secondary.

How do I play the Brand vs Kai'Sa matchup?

Use Meridian Zero's matchup analysis tool for detailed trading patterns, power spike windows, and win conditions for Brand vs Kai'Sa in Bot Lane. Both champions' optimal builds, runes, and skill orders are shown on this page.

Brand vs Kai'Sa Bot Lane

Q: What is the best build for Brand against Kai'Sa?

The optimal Brand build starts with Doran's Ring and Health Potion. Core items are Luden's Companion, Shadowflame, Rabadon's Deathcap with Sorcerer's Shoes. Run Arcane Comet from Sorcery with Inspiration secondary.

Patch 16.5 · Emerald+ Ranked · Meridian Zero Data

In the Brand vs Kai'Sa Bot Lane matchup on Patch 16.5, Brand has a 54.9% win rate (S tier) while Kai'Sa has a 49.1% win rate (S tier) in Emerald+ ranked games. Brand has the statistical edge with a 5.8% win rate advantage. Below are the optimal builds, runes, and skill orders for both champions in this matchup, sourced from OP.GG Emerald+ data.

Source: OP.GG Emerald+ ranked data, Patch 16.5 · Last updated: March 2026 · Meridian Zero Analytics

Brand

S Tier 54.9% WR

StartDoran's RingHealth Potion

CoreLuden's CompanionShadowflameRabadon's Deathcap

BootsSorcerer's Shoes

SpellsFlashHeal

SkillsQ > W > E

KeystoneArcane Comet

PrimarySorcery

SecondaryInspiration

Kai'Sa

S Tier 49.1% WR

StartDoran's BladeHealth Potion

CoreInfinity EdgePhantom DancerBloodthirster

BootsBerserker's Greaves

SpellsFlashHeal

SkillsQ > W > E

KeystoneLethal Tempo

PrimaryPrecision

SecondaryDomination

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Brand vs Kai'Sa Bot Lane

Brand

Kai'Sa

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